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CasNo: 67-71-0
Molecular Formula: C2H6O2S
Appearance: colourless crystals
Purification methods |
Using different purification methods, the products contained different impurities. in the finished product is different purification methods are also different. In general, it is decolored by active carbon, demineralized by ion exchange, and then recrystallized the solvent, dried by vacuum. After that, it is sieved and added an antistatic agent and a slip agent, in order to meet the export requirements. There is no national or ministerial standards. Currently, the countries in the world continue to enforce corporate standards or contract specifications. |
chemical synthesis |
Dimethyl sulfone is obtained by oxidizing methyl sulfone using nitric acid as oxidation. Methyl sulfone was oxidized at 140-145 ℃ by nitric oxide. After completion of the reaction, It was cooled and filtered to give white needles crude. Then vacuum distillation, collecting 138-145 ℃ (98.42kPa) distillate products which are the finished goods. |
Synthesis Reference(s) |
Journal of the American Chemical Society, 91, p. 3992, 1969 DOI: 10.1021/ja01042a075 |
Purification Methods |
Crystallise the sulfone from water. Dry it over P2O5. [Beilstein 1 IV 1279.] |
description |
Dimethyl Sulfone (MSM) is an organic sulfur-containing compound that occurs naturally in a variety of fruits, vegetables, grains, and animals including humans. a white, odorless, slightly bitter-tasting crystalline substance containing 34-percent elemental sulfur, MSM is a normal oxidative metabolite product of dimethyl sulfoxide (DMSO). Cow’s milk is the most abundant source of MSM, containing approximately 3.3 parts per million (ppm). Other foods containing MSM are coffee (1.6 ppm), tomatoes (trace to 0.86 ppm), tea (0.3 ppm), Swiss chard (0.05-0.18 ppm), beer (0.18 ppm), corn (up to 0.11 ppm), and alfalfa (0.07 ppm).MSM has been isolated from plants such as Equisetum arvense, also known as horsetail. Dimethyl Sulfone has the ability to enhance the body to produce insulin, while it can promote carbohydrate metabolism. It is essential for the synthesis of human collagen. It can not only promote wound healing, but also contribute for metabolic and neurological health requirement of vitamin B and vitamin C, biotin synthesis and activation, so it is known as "naturally beautiful carbon material". Dimethyl Sulfone exists in human skin, hair, nails, bones, muscles and various organs. Once people who are lack of it will get health disorders or diseases. It is the main substance for people to maintain the balance of biological sulfur. It has therapeutic value and healthcare function for people. It is an essential drug for human survial and health protection. |
application |
Dimethyl sulfone can eliminate the virus, enhance blood circulation, soften tissue, relieve pain, strengthen sinews and bones, calm the spirit, enhance physical strength, maintain skin, make beauty salons, treat the arthritis, oral ulcers, asthma and constipation, dredge the blood vessels, Clear gastrointestinal toxins. Dimethyl sulfone can be used as food and feed additives to supplement the organic sulfur nutrients for humans, pets and livestock. For external use, it can make the skin smooth, supple muscles, and reduce pigmentation. Recently, it surges in the amount as the cosmetic additives. In medicine, it has a good analgesic, it can promote wound healing and others. Dimethyl sulfone is a good penetrant in medicines production. |
Chemical properties |
white needle-like crystals. Melting point 109 ℃, boiling point 238 ℃, relative density 1.1702 (110/0 ℃), refractive index 1.4226, flash point 143 ℃. Soluble in water, ethanol, benzene, methanol and acetone, slightly soluble in ether and chloroform. Stink. |
InChI:InChI=1/C2H6O2S/c1-5(2,3)4/h1-2H3
In an effort to introduce N,N-dichloroar...
Oxidation of dimethyl sulfoxide with ben...
The kinetics and mechanism of picolinic ...
The article describes a synthesis of new...
The kinetics of oxidation of dimethylsul...
Kinetic relationships in oxidation of DM...
Magnetic personality: Nanocone nanoreact...
Kinetic relationships of the dimethyl su...
Reactivity of a palladium(II) peroxocarb...
In the picolinic acid (PA) promoted Crv!...
New heterogeneous catalysts comprising o...
Selective oxidation of thioethers is an ...
New oxovanadium and dioxomolybdenum Schi...
The invention discloses a synthesis meth...
5-phenyl-1,3-dithiane 1,1,3,3-tetraoxide
dimethylsulfone
bis(methylsulfonyl)methane
benzaldehyde
acetophenone
Conditions | Yield |
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With sodium hydroxide; at 100 ℃; for 8h; Product distribution;
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52 % Turnov. 11 % Turnov. |
dimethylsulfide
dimethylsulfone
dimethyl sulfoxide
Conditions | Yield |
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With C30H24N2O7W; dihydrogen peroxide; In dichloromethane; water; for 1h; Reflux;
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6% 94% |
With dihydrogen peroxide; In ethanol; hexane; water; at 60 ℃; for 0.0833333h;
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92% 6% |
With dihydrogen peroxide; In water; at 30 - 35 ℃; for 24h; Sealed tube; Green chemistry;
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68% 62% |
With 3-hydroperoxy-3-methyl-1-phenylindolin-2-one; In dichloromethane; for 2h; Heating;
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24% 49% |
With 1,1,4,4-Tetramethyl-2,3-dioxa-1,4-disilacyclohexane; In Petroleum ether; at 50 ℃; for 12h;
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19% 15% |
With tert.-butylhydroperoxide; aluminum tri-tert-butoxide; In benzene;
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17% |
With oxaziridinium salt 1; In [D3]acetonitrile; at 20 ℃;
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3 % Spectr. 94 % Spectr. |
With 3,3-bistrifluoromethyl-2-trifluoromethyl-oxaziridine; In chloroform-d1; trichlorofluoromethane; at -30 ℃; for 0.333333h;
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0.4 % Spectr. 75 % Spectr. |
With bis-[(trifluoroacetoxy)iodo]benzene; In chloroform; at 20 ℃; for 12h;
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15 % Spectr. 45 % Spectr. |
With dihydrogen peroxide; methyltrioxorhenium(VII); In chloroform-d1; at 20 ℃; for 24h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
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With ozone; In solid matrix; at -263.2 ℃; Mechanism; Irradiation; also methanethiol;
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With dihydrogen peroxide; methyltrioxorhenium(VII); In chloroform-d1; at 20 ℃; for 24h; Product distribution; reactions of derivatives under var. conditions;
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With dihydrogen peroxide; In water; at 19.9 ℃; Product distribution; Mechanism; Kinetics; other reagents, pH dependence;
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With oxaziridinium salt 1; In [D3]acetonitrile; at 20 ℃; for 1.5h;
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10 % Spectr. 90 % Spectr. |
With dihydrogen peroxide; Further Variations:; Temperatures; molar ratio; Product distribution;
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With cis-
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68 % Chromat. 9 % Chromat. |
With dihydrogen peroxide; at 5 ℃; for 0.166667h; Further Variations:; Temperatures; Product distribution;
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With nitric acid; In acetonitrile; at 20 ℃; for 15h; chemoselective reaction;
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With dihydrogen peroxide; In methanol; at 20 ℃; for 0.25h; chemoselective reaction;
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With dihydrogen peroxide; In acetonitrile; at 20 ℃; for 0.5h;
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With C38H26N6NiS2(2+)*2NO3(1-); dihydrogen peroxide; In water; acetonitrile; at 20 ℃;
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With 3-chloro-benzenecarboperoxoic acid; In chloroform-d1;
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With (η5-C5H5)Mo(CO)3C2Ph; dihydrogen peroxide; In acetonitrile; at 20 ℃; for 2h; Inert atmosphere; Schlenk technique;
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With dihydrogen peroxide; In acetonitrile; at 20 ℃; for 1h; Catalytic behavior;
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With ozone; In acetone; at 60 ℃; for 2h; under 3750.38 Torr; Solvent; Pressure; Temperature; Reagent/catalyst;
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With bismuth oxybromide; oxygen; In acetonitrile; for 12h; under 750.075 Torr; Irradiation;
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With dihydrogen peroxide; In methanol; at 30 ℃; for 600h; under 1125.11 Torr; Reagent/catalyst; Solvent; Temperature; Molecular sieve;
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With dihydrogen peroxide; [Ni0.5(1-vinylimidazole)2]3[Ni0.5(1-vinylimidazole)H2O][V4O12]*H2O; In ethanol; water; at 45 ℃; for 4h;
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With water; dihydrogen peroxide; C16H17MoN3O6; In ethanol;
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dimethylsulfide
2-(methylsulfonyl)acetic acid
sulfonyldiacetic acid
1-methyl-4-nitrosobenzene
2-methylsulfonyl-1-phenylethanone
2-(2-Hydroxy-2,2-diphenyl-ethanesulfonyl)-1,1-diphenyl-ethanol
2-Imino-3-methylbutyl-methylsulfon
o-Methylsulfonylacetylphenylessigsaeure