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Praziquantel

  • Product Name: Praziquantel
  • CasNo: 55268-74-1
  • Purity:
  • Appearance: White or practically white crystalline powder

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Email:libbywu@fellowchemical.com

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CasNo： 55268-74-1

Molecular Formula： C19H24N2O2

Appearance： White or practically white crystalline powder

Factory Supply High Purity 99% 55268-74-1 Praziquantel with Efficient Delivery

  • Molecular Formula:C19H24N2O2
  • Molecular Weight:312.412
  • Appearance/Colour:White or practically white crystalline powder 
  • Melting Point:136-138 °C 
  • Refractive Index:1.5600 (estimate) 
  • Boiling Point:544.1 °C at 760 mmHg 
  • PKA:-0.98±0.20(Predicted) 
  • Flash Point:254.6 °C 
  • PSA：40.62000 
  • Density:1.22 g/cm3 
  • LogP:2.41070 

Praziquantel 55268-74-1 Factory

Praziquantel is the drug of choice for the treatment of all forms of schistosomiasis. Ningbo Zhenhai Fellow Chemical Co.,Ltd was estabilished in 2010, which is professional supplier of Chemical Raw Material and Intermediates. We also help our client to extend the business of pyridine derivatives in domestic and abroad in the past 15years. Now we have three factories located in Zhejiang, Henan and Ningxia for the producing of Chemical Raw Material and Intermediates. With good product quality and excellent service, our products have been sold to cities all over the country, and also abroad.

55268-74-1 Relevant articles

Towards an understanding of the mechanism of action of praziquantel

Anthony D. Aragon a, Reza A. Imani a, Vint R. Blackburn a, Pauline M. Cupit a, Sandra D. Melman a, Tinopiwa Goronga b, Thomas Webb b, Eric S. Loker a, Charles Cunningham a

, Molecular and Biochemical Parasitology Volume 164, Issue 1, March 2009, Pages 57-65

Although praziquantel (PZQ) has been used to treat schistosomiasis for over 20 years its mechanism of action remains unknown. We have developed an assay based on the transcriptional response of Schistosoma mansoni PR-1 to heat shock to confirm that while 6-week post-infection (p.i.) schistosomes are sensitive to PZQ, 4-week p.i. schistosomes are not.

The little we know about the pharmacokinetics and pharmacodynamics of praziquantel (racemate and R-enantiomer)

Piero Olliaro, Petra Delgado-Romero, Jennifer Keiser

, Journal of Antimicrobial Chemotherapy, Volume 69, Issue 4, April 2014, Pages 863–870

Recently, there has been a renewed interest in studying better formulations of praziquantel, especially for small children. This stems, at least in part, from the fact that preschool-aged children are now recognized as a vulnerable population and a group for targeted treatment.

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