Buy Reliable Quality Quality Manufacturer Supply 2'-Hydroxyacetophenone 118-93-4 with the Best Price
- Molecular Formula:C8H8O2
- Molecular Weight:136.15
- Appearance/Colour:Light yellow liquid
- Vapor Pressure:~0.2 mm Hg ( 20 °C)
- Melting Point:3-6 °C(lit.)
- Refractive Index:n20/D 1.558(lit.)
- Boiling Point:218.4 °C at 760 mmHg
- PKA:10.06(at 25℃)
- Flash Point:87.5 °C
- PSA：37.30000
- Density:1.131 g/cm3
- LogP:1.59480
2'-Hydroxyacetophenone(Cas 118-93-4) Usage
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Reference
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Bhaw-Luximon, A.; Jhurry, D.; Spassky, N., Controlled polymerization of DL-lactide using a Schiff's base al-alkoxide initiator derived from 2-hydroxyacetophenone. Polym. Bull. 2000, 44, 31-38. Johann Wonschick; Clemens M. Putter; Keepe, E., TASTE MODIFYING COMPOSITIONS PCT WO 2016/103183 A1 2016. Alexander J Bridges; Saltiel, A. R., 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders US Patent US5525625 1996.
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Preparation
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Preparation by Fries rearrangement of phenyl acetate, with Lewis acidsaluminium chloride.
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Synthesis Reference(s)
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Tetrahedron Letters, 24, p. 377, 1983 DOI: 10.1016/S0040-4039(00)81412-4
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Aroma threshold values
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Detection: 5.5 ppm; aroma characteristics at 2.0%: phenolic, sharp, benzaldehyde, cherry pit, tropical, melon with a tobacco afternote
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Taste threshold values
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Taste characteristics at 5.0 ppm: naphthyl, cinnamon, cherry pit, coumarin, phenolic, tobacco and honey.
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General Description
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Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
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Consumer Uses
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ECHA has no public registered data indicating whether or in which chemical products the substance might be used. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.
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118-93-4 Relevant articles
Preparation method of O-methoxyacetophenone
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Paragraph 0027; 0029, (2021/02/10)
The invention relates to a preparation m...
Method for preparing o-methoxyacetophenone through catalytic distillation
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Paragraph 0026; 0028, (2021/02/10)
The invention relates to a method for pr...
Bioactivity study of thiophene and pyrazole containing heterocycles
Athare, Anil E.,Dare, Sushama B.,Kale, Nitin V.,Karale, Bhausaheb K.,Mhaske, Sadhana D.,Salve, Supriya P.,Takate, Sushama J.
, p. 891 - 899 (2021/09/08)
Chalcones 3a-f were prepared by reacting...
Chromone dioxadiazole compound as well as preparation method and application thereof
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Paragraph 0021-0023, (2021/10/30)
The preparation method comprises the fol...
118-93-4 Process route
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- 93-56-1
phenylethane 1,2-diol
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- 15206-55-0
methyl 2-oxo-2-phenylacetate
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- 118-93-4,104809-67-8
o-hydroxyacetophenone
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- 611-73-4
Benzoylformic acid
Conditions
| Conditions |
Yield |
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With sodium tetrahydroborate; 1% Pd/C; water; potassium hydroxide; In methanol; at 20 ℃; for 9h; In air;
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47%
43%
9% |
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- 78812-94-9
1-(2-acetoxyphenyl)vinyl acetate
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- 5751-48-4
2-methylchromone
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- 7250-94-4
o-acetoxyacetophenone
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- 118-93-4,104809-67-8
o-hydroxyacetophenone
Conditions
| Conditions |
Yield |
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In benzene; Irradiation;
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25%
5%
20% |
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In benzene; Mechanism; Irradiation;
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20%
25%
5% |
118-93-4 Upstream products
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21535-97-7
3-methyl-benzofuran
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491-38-3
1-benzopyran-4(4H)-one
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141-52-6
sodium ethanolate
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917-64-6
methyl magnesium iodide
118-93-4 Downstream products
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579-74-8
2-Methoxyacetophenone
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36695-15-5
1-[2-(4-nitrobenzoyloxy)-phenyl]-ethanone
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6323-86-0
N-(2-hydroxyphenacyl)pyridinium iodide
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17451-00-2
3-acetyl-4-methyl-2H-1-benzopyran-2-one
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